Functional Reconstitution of Thymopoiesis after Human Immunodeficiency Virus Infection
AUTOR(ES)
Kitchen, Scott G.
FONTE
American Society for Microbiology
RESUMO
We have utilized combination antiretroviral therapy following human immunodeficiency virus type 1-induced human CD4+ thymocyte depletion in the SCID-hu mouse to examine the immune competence of reconstituting thymocytes which appear following administration of combination therapy. These cells express a normal distribution of T-cell receptor variable gene families and are responsive to costimulatory signals. These results suggest that normal thymic function may be restored following antiretroviral treatment.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=111790Documentos Relacionados
- Emergency Medicine: Zidovudine for Prophylaxis of Human Immunodeficiency Virus Infection After Accidental Exposure
- Resumption of virus production after human immunodeficiency virus infection of T lymphocytes in the presence of azidothymidine.
- Pathogenesis of human immunodeficiency virus infection.
- Functional reconstitution of influenza virus envelopes.
- Pediatric human immunodeficiency virus infection.
