Genetic Characterization of Mutations Which Affect Catabolite-Sensitive Operons in Escherichia coli, Including Deletions of the Gene for Adenyl Cyclase
AUTOR(ES)
Brickman, Edith
RESUMO
Sixty-two spontaneous mutations have been characterized which reduce the level of expression of catabolite-sensitive operons. These mutations appear to affect either the crp (catabolite gene activator protein) or cya (adenyl cyclase) loci. No new loci have been discovered. Deletions of the cya gene do not remove an essential function. φ80 transducing phage for the cya gene have been used to do recombination and complementation studies on cya mutants.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=285421Documentos Relacionados
- Transcriptional regulation of the heat shock regulatory gene rpoH in Escherichia coli: involvement of a novel catabolite-sensitive promoter.
- The catabolite-sensitive promoter for the chloramphenicol acetyl transferase gene is preceded by two binding sites for the catabolite gene activator protein.
- Mechanism of Activation of Catabolite-Sensitive Genes: A Positive Control System*
- Transient repression of catabolite-sensitive enzyme synthesis elicited by 2,4-dinitrophenol.
- ISOLATION OF ADENYL CYCLASE FROM Escherichia coli*
