Genetic controls of meiotic recombination and somatic DNA metabolism in Drosophila melanogaster.

AUTOR(ES)

Baker, B S

RESUMO

Recombination-defective meiotic mutants and mutagen-sensitive mutants of D. melanogaster have been examined for their effects on meiotic chromosome behavior, sensitivity to killing by mutagens, somatic chromosome integrity, and DNA repair processes. Several loci have been identified that specify functions that are necessary for both meiotic recombination and DNA repair processes, whereas mutants at combination and DNA repair processes, whereas mutants at other loci appear to be defective in only one pathway of DNA processing.

Documentos Relacionados

• Genetic Change of Recombination Value in DROSOPHILA MELANOGASTER. II. Simulated Natural Selection
• Overexpression of a Rrp1 transgene reduces the somatic mutation and recombination frequency induced by oxidative DNA damage in Drosophila melanogaster.
• MEIOTIC DRIVE IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER. II. GENETIC VARIATION AT THE SEGREGATION-DISTORTER LOCUS*
• Chromosomal Sites Necessary for Normal Levels of Meiotic Recombination in DROSOPHILA MELANOGASTER. I. Evidence for and Mapping of the Sites
• Genetic Change of Recombination Value in DROSOPHILA MELANOGASTER. I. Artificial Selection for High and Low Recombination and Some Properties of Recombination-Modifying Genes