Genetic variation in serum low density lipoproteins and lipid levels in man.
AUTOR(ES)
Berg, K
RESUMO
Combined data from 10 different populations indicate that the serum cholesterol and triglyceride levels are higher in Ag(x-) than in Ag(x+) individuals. Although the differences were relatively small, they became more pronounced with increasing age. The Ag(x) antigen, which is associated with the serum low density lipoprotein, is genetically controlled and the present study therefore has revealed a small but significant effect of a single autosomal locus on lipids implicated in the pathogenesis of atherosclerosis. No explanation of the higher cholesterol and triglyceride levels in Ag(x-) than in Ag(x+) persons is apparent.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=336035Documentos Relacionados
- Very low density lipoproteins stimulate surfactant lipid synthesis in vitro.
- Immunoregulation by low density lipoproteins in man. Inhibition of mitogen-induced T lymphocyte proliferation by interference with transferrin metabolism.
- Receptor-mediated Catabolism of Low Density Lipoprotein in Man. QUANTITATION USING GLUCOSYLATED LOW DENSITY LIPOPROTEIN
- Metabolic relationships among the plasma lipoproteins: Reciprocal changes in the concentrations of very low and low density lipoproteins in man
- Parallel variation of ventricular CSF tryptophan and free serum tryptophan in man.