Genetics of Cycloheximide Resistance in Tetrahymena
AUTOR(ES)
Bleyman, Lea K.
RESUMO
Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro- and macro-nuclei of this organism for genetic studies.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1213740Documentos Relacionados
- Macronuclear Genetics of Tetrahymena. II. Macronuclear Location of Somatic Mutations to Cycloheximide Resistance
- Isolation and Genetic Characterization of a Mutation Affecting Ribosomal Resistance to Cycloheximide in Tetrahymena
- Induced Resistance to 6-Methylpurine and Cycloheximide in Tetrahymena. I. Germ Line Mutants of T. THERMOPHILA
- Transformation of Tetrahymena to cycloheximide resistance with a ribosomal protein gene through sequence replacement.
- Induced Resistance to 6-Methylpurine and Cycloheximide in Tetrahymena. II. Variation within Vegetative Cultures of Micronucleate T. THERMOPHILA and Amicronucleate T. PYRIFORMIS