Glucosamine Resistance in Yeast. I. a Preliminary Genetic Analysis
AUTOR(ES)
Ball, A. J. S.
RESUMO
Mutants of the yeast Saccaromyces cerevisiae which can grow on glycerol medium in the presence of 0.05% D (+) glucosamine have been isolated. Genetic analysis of 13 of these glucosamine resistant (GR) mutants demonstrated two modes of inheritance. One group of mutants (GR 5, 6, 7, 8, 9 and 10) gave results characteristic of non-Mendelian inheritance and it is suggested that these mutants represent one or more new mitochondial loci. Four of the remaining mutants showed clear-cut Mendelian inheritance. These mutants fell into two complementation groups and subsequent mapping experiments demonstrated that two independent loci, gay 1 and gay 2, unlinked to each other or to the centromeres of chromosomes I, II, IV, VIII or IX, were responsible for conferring glucosamine resistance in these mutants.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1213578Documentos Relacionados
- Genetic Analysis of Gamma-Ray Mutagenesis in Yeast. I. Reversion in Radiation-Sensitive Strains
- Respiration-Deficient Mutants of Yeast. I. Genetics
- Dominant mutation for nystatin resistance in yeast.
- Genetic analysis of Cln/Cdc28 regulation of cell morphogenesis in budding yeast.
- Foreign transcriptional enhancers in yeast. I. Interactions of papovavirus transcriptional enhancers and a quiescent pseudopromoter on supercoiled plasmids.
