Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig.
AUTOR(ES)
Niijima, A
RESUMO
1. Afferent discharges were recorded from nerve filaments dissected from the hepatic branch of the vagus nerve in the guinea-pig in situ. 2. A significant decrease in the discharge rate was observed following the administration of D-glucose into the portal vein but not after the administration of D-mannose, D-fructose, D-galactose, L-glucose, D-xylose or D-arabinose. 3. The mean discharge rate of these fibres was inversely related to the concentration of glucose in the portal blood. 4. These results suggest the existence of D-glucose 'sensors' in the liver which monitor the glucose concentration of portal blood.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1197400Documentos Relacionados
- Ryanodine-sensitive calcium stores involved in neurotransmitter release from sympathetic nerve terminals of the guinea-pig.
- Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig.
- Effects of sympathetic nerve stimulation on the sino-atrial node of the guinea-pig.
- Pharmacological evidence for L-aspartate as the neurotransmitter of cerebellar climbing fibres in the guinea-pig.
- Mechanically evoked responses of afferent fibres innervating the guinea-pig's ureter: an in vitro study.
