Granulocytic Ehrlichiosis in Mice Deficient in Phagocyte Oxidase or Inducible Nitric Oxide Synthase
AUTOR(ES)
Banerjee, Rila
FONTE
American Society for Microbiology
RESUMO
Mice deficient in phox (gp91phox−/−) or NOS2 (NOS2−/−) were infected with the agent of human granulocytic ehrlichiosis (HGE) to evaluate the importance of these pathways in the eradication of HGE bacteria. NOS2−/− mice had delayed clearance of the HGE agent in comparison to control or gp91phox−/− mice, suggesting that reactive nitrogen intermediates play a role in the early control of HGE.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=101771Documentos Relacionados
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