Household pets as a potential reservoir for Clostridium difficile infection.
AUTOR(ES)
Borriello, S P
RESUMO
The purpose of this study was to assess the carriage of Clostridium difficile by household pets to determine their potential as a reservoir of infection. The selective cycloserine-cefoxitin medium was used for C difficile isolation, and tissue culture used for detection of cytotoxin. Carriage of C difficile by household pets was found to be common (23%). The carriage tends to be transient and does not appear to be associated with gastrointestinal disease. Although carriage was higher in animals who had antecedent antibiotic treatment (31%) compared to those which had not (19%), the differences were not statistically significant. In most cases non-cytotoxigenic strains were isolated. Of the cytotoxigenic strains isolated at least one strain was pathogenic in a well documented animal model of human disease. Both cytotoxigenic and non-cytotoxigenic strains of C difficile could be isolated from the environment of the animals studied.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=498110Documentos Relacionados
- Isolation of Clostridium difficile from human jejunum: identification of a reservoir for disease?
- Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection.
- Bartonella Infection in Animals: Carriership, Reservoir Potential, Pathogenicity, and Zoonotic Potential for Human Infection
- Clostridium difficile infection in hospitals: a brewing storm
- Clostridium difficile infection of the gut.