Identification of channel-forming activity in the cell wall of Corynebacterium glutamicum.
AUTOR(ES)
Niederweis, M
RESUMO
The cell wall of the gram-positive Corynebacterium glutamicum was prepared. It contained an ion-permeable channel with a single-channel conductance of about 6 nS in 1 M KCl. The mobility sequence of the ions in the channel is similar to that in the aqueous phase, suggesting that it is a water-filled channel wide enough to allow unhindered diffusion of ions. The results indicate that we have identified the hydrophilic pathway through the mycolic acid layer of C. glutamicum.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=177387Documentos Relacionados
- Channel-Forming (Porin) Activity in Herpetosiphon aurantiacus Hp a2
- The Cell Wall of the Pathogenic Bacterium Rhodococcus equi Contains Two Channel-Forming Proteins with Different Properties
- Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers.
- Identification of an ion channel-forming motif in the primary structure of CFTR, the cystic fibrosis chloride channel.
- Biochemical Identification and Biophysical Characterization of a Channel-Forming Protein from Rhodococcus erythropolis