Identification of the major antigenic determinants on lipoglycans from Acholeplasma granularum and Acholeplasma axanthum.

AUTOR(ES)

Al-Samarrai, T H

RESUMO

The major antigenic determinants of the lipoglycans from Acholeplasma granularum and Acholeplasma axanthum were found to be the oligosaccharide sequences Glcp(beta 1 leads to 2)-Glcp(alpha 1 leads to 4)-Glcp and Glcp(beta 1 leads to 2)-Glcp(beta 1 leads to 2)-Glcp, respectively. The disaccharides sophorose and maltose inhibited hemagglutination by specific antiserum of sheep erythrocytes coated with lipoglycan from A. granularum. Only sophorose possessed this capacity with the lipoglycan from A. axanthum. Periodate oxidation destroyed the ability of both lipoglycans to interact with specific antibody, a result compatible with structural data on the lipoglycans.

Documentos Relacionados

• Existence of carotenoids in Acholeplasma axanthum.
• Identification of the Amide-Linked Fatty Acids of Acholeplasma axanthum S743 as d(–)3-Hydroxyhexadecanoate and Its Homologues
• Acholeplasma axanthum, sp. n.: a New Sterol-Nonrequiring Member of the Mycoplasmatales
• Multiple antigenic determinants on the major surface glycoprotein of murine mammary tumor viruses.
• Identification of lambda gt11 clones encoding the major antigenic determinants expressed by Theileria parva sporozoites.