Identification of the purC gene product of Escherichia coli.
AUTOR(ES)
Parker, J
RESUMO
The purC region of the Escherichia coli chromosome was isolated from in vivo-derived lambda transducing bacteriophages and cloned in high-copy-number plasmids. The product of the purC gene, phosphoribosylaminoimidazolesuccinocarboxamide synthetase, was identified as a protein with an Mr of ca. 27,000. The level of the protein is increased by more than 60-fold in strains carrying the gene on a high-copy-number plasmid. Purine addition represses the enzyme level in both plasmid- and non-plasmid-containing strains.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=215316Documentos Relacionados
- Identification of a purC gene from Streptococcus pneumoniae.
- DNA sequence of the purC gene encoding 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthetase and organization of the dapA-purC region of Escherichia coli K-12.
- Identification of the rodA gene product of Escherichia coli.
- Identification of the enzymatic reactions encoded by the purG and purI genes of Escherichia coli.
- Identification of the heat-inducible protein C15.4 as the groES gene product in Escherichia coli.