Immune reactivity of Visna virus-inoculated mice.
AUTOR(ES)
Svennerholm, B
RESUMO
Visna virus inoculation of mice before immunization with unrelated antigens caused suppression of humoral and cell-mediated immune responses. The immunosuppressive effect was dependent on the virus dose and time of administration. The number of "background" antibody-producing spleen cells increased slightly after inoculation of Visna virus. Heat treatment of Visna virus abolished its immunosuppressive effect. Replication of Visna virus in mice seemed to be a prerequisite for its immunomodulating effect.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=421871Documentos Relacionados
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