Impairment of cell division of Trypanosoma cruzi epimastigotes

AUTOR(ES)
FONTE

Memórias do Instituto Oswaldo Cruz

DATA DE PUBLICAÇÃO

2007-02

RESUMO

The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T. cruzi.

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