In Vitro Activities of New Quinolones and Oxazolidinones against Actinomadura madurae

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

In this work, we studied the in vitro sensitivity of 24 strains of Actinomadura madurae to a new oxazolidinone (DA-7867), gatifloxacin, moxifloxacin, and garenoxacin by using a broth microdilution method. We observed that the A. madurae strains had a high level of sensitivity to all the antimicrobials tested. The most active drug was DA-7867, with a MIC at which 90% of the strains are inhibited (MIC90) of 0.125 μg/ml and a MIC50 of 0.06 μg/ml.

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