In Vitro Activities of Trioxaquines against Schistosoma mansoni▿

AUTOR(ES)

Boissier, Jérôme

FONTE

American Society for Microbiology (ASM)

RESUMO

We report the in vitro activities of trioxaquines against larval and adult-stage schistosomes at 5 and 50 μg/ml, respectively. Such activities are equivalent to that of praziquantel, the major and rather unique drug currently used for the treatment of schistosomiasis. In this range of concentrations, artemisinin derivatives (artesunate and artemether) have no activity.

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