In Vitro Activity of a New 8-Methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae
AUTOR(ES)
Roblin, Patricia M.
FONTE
American Society for Microbiology
RESUMO
The in vitro susceptibilities of 10 strains of Chlamydia pneumoniae to a new 8-methoxyquinolone, BAY 12-8039, and to ofloxacin, doxycycline, and erythromycin were determined. The activity of BAY 12-8039 was similar to that of ofloxacin, with a MIC at which 90% of the isolates had no inclusions and a minimal chlamydicidal concentration at which 90% of the isolates had no inclusions after passage of 1.0 μg/ml, but this activity was less than those of doxycycline and erythromycin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105577Documentos Relacionados
- In vitro activity of Bay 12-8039, a new 8-methoxyquinolone.
- In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
- In Vitro Activity of BAY 12-8039, a New Fluoroquinolone, against Mycoplasmas
- In vitro activity of BAY 12-8039, a new fluoroquinolone.
- Moxifloxacin (BAY12-8039), a New 8-Methoxyquinolone, Is Active in a Mouse Model of Tuberculosis
