In vitro activity of Bay 12-8039, a new 8-methoxyquinolone.
AUTOR(ES)
Fass, R J
RESUMO
MICs of Bay 12-8039 and comparative antimicrobials were determined for 820 recent clinical isolates. Ciprofloxacin was approximately 2-fold more active than Bay 12-8039 and ofloxacin against Enterobacteriaceae and approximately 8-fold more active against Pseudomonas aeruginosa. Bay 12-8039 was approximately 2- to 16-fold more active than ciproiloxacin and ofloxacin against nonfermenters (except P. aeruginosa), staphylococci, streptococci, enterococci, and anaerobes. As determined by regression analysis, there was a high degree of correlation among quinolone MICs.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=164014Documentos Relacionados
- In Vitro Activity of a New 8-Methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae
- In vitro activity of BAY 12-8039, a new fluoroquinolone.
- In Vitro Activity of BAY 12-8039, a New Fluoroquinolone, against Mycoplasmas
- In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
- Moxifloxacin (BAY12-8039), a New 8-Methoxyquinolone, Is Active in a Mouse Model of Tuberculosis
