In Vitro and in Vivo Combinations of Cefotaxime and Minocycline against Aeromonas hydrophila
AUTOR(ES)
Ko, Wen-Chien
FONTE
American Society for Microbiology
RESUMO
The activities of cefotaxime and minocycline against Aeromonas hydrophila were investigated. Cefotaxime (4 times the MIC) plus minocycline (0.75 times the MIC) elicited an inhibitory effect for 48 h in a time-kill study, and more infected mice treated with both drugs survived (91%) than survived after treatment with cefotaxime (9%) or minocycline (44%) alone, suggesting that cefotaxime and minocycline act synergistically against A. hydrophila.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=90456Documentos Relacionados
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