In vitro responses of guinea pig peritoneal macrophages to Legionella pneumophila.
AUTOR(ES)
Kishimoto, R A
RESUMO
Transmission and scanning electron microscopy were used to study the phagocytosis of virulent and avirulent strains of Legionella pneumophila. The interaction between L. pneumophila and peritoneal macrophages from normal guinea pigs or from animals that had survived infection was studied. The virulent strains survived and proliferated within the phagocyte after ingestion by either type of macrophage, whereas the avirulent strain of bacteria was killed by normal macrophages. Although the addition of immune serum enhanced phagocytosis, the outcome was the same as with normal serum.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=351444Documentos Relacionados
- Interaction of primate alveolar macrophages and Legionella pneumophila.
- Adherence of Legionella pneumophila to guinea pig peritoneal macrophages, J774 mouse macrophages, and undifferentiated U937 human monocytes: role of Fc and complement receptors.
- Human and guinea pig immune responses to Legionella pneumophila protein antigens OmpS and Hsp60.
- Fate of Legionella pneumophila Philadelphia-1 strain in resident, elicited, activated, and immune peritoneal macrophages of guinea pigs.
- Effects of alpha-amylase on in vitro growth of Legionella pneumophila.
