In Vitro Susceptibilities of Mycoplasma hominis to Six Fluoroquinolones as Determined by E Test

AUTOR(ES)

Waites, Ken B.

FONTE

American Society for Microbiology

RESUMO

Twenty isolates of Mycoplasma hominis were tested for their susceptibility to six fluoroquinolones by the E test. The MICs at which 90% of the isolates were inhibited (in micrograms per milliliter) were as follows: sparfloxacin, 0.031; clinafloxacin, moxifloxacin, and trovafloxacin, 0.063; levofloxacin, 0.25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or incubation in CO2 elevated MICs by ≤1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and microbroth dilution for M. hominis.

Documentos Relacionados

• In Vitro Development of Resistance to Six and Four Fluoroquinolones in Mycoplasma pneumoniae and Mycoplasma hominis, Respectively
• In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.
• Characterization of Mycoplasma hominis mutations involved in resistance to fluoroquinolones.
• Molecular mechanism of fluoroquinolones resistance in Mycoplasma hominis clinical isolates
• In Vitro Antibiotic Susceptibilities of Burkholderia mallei (Causative Agent of Glanders) Determined by Broth Microdilution and E-Test