Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation.
AUTOR(ES)
Patel, U D
RESUMO
Inactivation of aflatoxin B1 was studied by using gamma radiation and hydrogen peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate 50 micrograms of aflatoxin B1 in the presence of 5% hydrogen peroxide, and 400 krad was required for total degradation of 100 micrograms of aflatoxin in the same system. Degradation of aflatoxin B1 was confirmed by high-pressure liquid chromatographic and thin-layer chromatographic analysis. Ames microsomal mutagenicity test showed loss of aflatoxin activity. This method of detoxification also reduces the toxin levels effectively in artificially contaminated groundnuts.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=184132Documentos Relacionados
- Sensitivity of aflatoxin b1 to ionizing radiation.
- Inactivation of rabies diagnostic reagents by gamma radiation.
- Quantitation of aflatoxin B1 and aflatoxin B1 antibody by an enzyme-linked immunosorbent microassay.
- Effect of Aflatoxin B1 on Cell Cultures1
- Interconversion of aflatoxin B1 and aflatoxicol by several fungi.