Inactivation of poliovirus and other enteroviruses by solutions of sodium fluoride at low pH.
AUTOR(ES)
Eubanks, R D
RESUMO
Solutions of sodium fluoride at pH 3 to 4 inactivated enteroviruses, whereas other sodium salts had little or no effect on virus infectivity. Solutions of potassium fluoride also inactivated viruses under similar conditions. Light, temperature, and the presence of organic compounds such as detergents and fecal matter did not affect inactivation of virus by 0.4 M solutions of sodium fluoride at pH 3. to 4. Decreasing the sodium fluoride concentration below 0.04 M or raising the pH above 4 reduced the viricidal properties of the solutions. Virus adsorbed to membrane filters and sludge flocs could not be recovered after treatment of solids-associated virus with solutions of sodium fluoride.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=243760Documentos Relacionados
- Requirements for entry of poliovirus RNA into cells at low pH.
- Viral aggregation: effects of salts on the aggregation of poliovirus and reovirus at low pH.
- Viral aggregation: buffer effects in the aggregation of poliovirus and reovirus at low and high pH.
- Metastable intermediates in myoglobin at low pH.
- Synthesis and activity of Helicobacter pylori urease and catalase at low pH.
