Influence of processing parameters on structural characteristics of porous calcium phosphate samples: a study using an experimental design method

AUTOR(ES)

Ugarte, José Fernandes de Oliveira, Sena, Lidia Ágata de, Pérez, Carlos André de Castro, Aguiar, Paula Fernandes de, Rossi, Alexandre Malta, Soares, Glória Almeida

FONTE

Materials Research

DATA DE PUBLICAÇÃO

2005-03

RESUMO

Synthetic porous ceramics can be used as three-dimensional scaffolds for bone repair. The aim of this work is to correlate process parameters with scaffolds structural characteristics. The factorial 2 level experimental design was chosen to study the effect of the Ca/P ratio (1.58 or 1.67), calcination temperature (1000 or 1150 °C) and porogen content (20 or 40%) on the calcium phosphate samples characteristics. The influence of such parameters was determined by X-ray diffraction, infrared spectroscopy and image analysis. It was observed that phase composition was basically a function of the Ca/P ratio of the raw material. The use of the porogen did not alter the hydroxyapatite (HA)/tricalcium phosphate (TCP) content, but induced changes in the relative content of TCP phase (alpha or beta). It is possible to design a porous sample with defined characteristics, and the model herein used can be considered as having a good predictive power.

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