Infusing Lipid Raises Plasma Free Fatty Acids and Induces Insulin Resistance in Muscle Microvasculature

AUTOR(ES)

Liu, Zhenqi

FONTE

The Endocrine Society

RESUMO

Context: Insulin recruits muscle microvasculature, which increases the endothelial exchange surface area to facilitate substrate delivery. Elevated plasma concentrations of free fatty acids (FFAs) cause insulin resistance.

Documentos Relacionados

• Role of free fatty acids and insulin in determining free fatty acid and lipid oxidation in man.
• Fatty Acids, Insulin Resistance, and Protein Metabolism
• Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action
• THE ROLE OF PLASMA FREE FATTY ACIDS IN DEVELOPMENT OF FATTY LIVER
• Muscle Contraction, but Not Insulin, Increases Microvascular Blood Volume in the Presence of Free Fatty Acid–Induced Insulin Resistance