Inhibition of a common human anti-hepatitis B surface antigen idiotype by a cyclic synthetic peptide.
AUTOR(ES)
Kennedy, R C
RESUMO
A common human anti-hepatitis B surface antigen idiotype-anti-idiotype reaction was partially inhibited by a cyclic synthetic hepatitis B surface antigen peptide. Reduction of the intrachain disulfide bond and subsequent alkylation destroyed its inhibitory activity, suggesting that a conformation-dependent group alpha epitope was associated with this cyclic peptide.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=255172Documentos Relacionados
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