Inhibitory effect of syphilitic rabbit serum on DNA synthesis in rabbit cells in vitro.

AUTOR(ES)

Wong, G H

RESUMO

A previously described toxic factor associated with Treponema pallidum (Nichols) and found in extracts of syphilitic rabbit testes has now also been detected in syphilitic rabbit serum. The toxic factor, which inhibits DNA synthesis in baby rabbit genital organ (BRGO) cells in vitro, is present in rabbit serum up to 30 days after infection with T pallidum.

Documentos Relacionados

• Effect of four serum components on survival of Treponema pallidum and its attachment to rabbit cells in vitro.
• The effect of Streptomycin on antibody synthesis in vitro.
• The nonspecific inhibitory effect of synovial tissue extracts on leucocyte migration in vitro.
• Insulin-dependent DNA polymerase and DNA synthesis in mammary epithelial cells in vitro.
• Inhibitory effects of volume expansion performed in vivo on transport in the isolated rabbit proximal tubule perfused in vitro.