Inhibitory Effects of Mitomycin-Related Compounds Lacking the C1-C2 Aziridine Ring
AUTOR(ES)
Mercado, Carmen M.
RESUMO
Three chemical derivatives of mitomycin C cause loss of viability, inhibition of deoxyribonucleic acid synthesis, and inhibition of cell division in bacteria. Each of these drugs lacks the C1-C2 aziridine ring previously postulated to be essential for the bactericidal effect of mitomycin C.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=444168Documentos Relacionados
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