Initiation and Direction of RNA Transcription by Vesicular Stomatitis Virus Virion Transcriptase
AUTOR(ES)
Roy, Polly
RESUMO
The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along the template RNA. By the use of sequential labeling techniques and exonucleases, it has been determined that there is a 5′ to 3′ direction of product RNA synthesis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=355129Documentos Relacionados
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