Initiation of Hemoglobin Synthesis: Comparison of Model Reactions That Use Artificial Templates with Those Using Natural Messenger RNA

AUTOR(ES)
RESUMO

Partial reactions designed to study the individual steps in the initiation of protein synthesis may be divided into two groups: artificial models using artificial mRNA templates and natural models using naturally occurring mRNA. The requirements for each of the reticulocyte initiation factors, IF-M1, IF-M2, and IF-M3, and for GTP are examined using these models in order to determine if either type of model is a valid representation of the events occurring in natural initiation.

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