Interaction of Listeria monocytogenes with Human Brain Microvascular Endothelial Cells: an Electron Microscopic Study
AUTOR(ES)
Greiffenberg, Lars
FONTE
American Society for Microbiology
RESUMO
Internalization of Listeria monocytogenes into human brain microvascular endothelial cells (HBMEC) has recently been demonstrated to be dependent upon the inlB gene. In the present scanning electron microscopic study we show that L. monocytogenes efficiently interacts with the surface of HBMEC in an inlB-independent manner which is also different from invasion. The inlB-dependent invasion of HBMEC by L. monocytogenes is accompanied by intracellular multiplication, movement, and production of bacterium-containing protrusions. These protrusions extend from the cell surface without perturbation of any adjacent cellular membrane.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97578Documentos Relacionados
- Interaction of Listeria monocytogenes with Human Brain Microvascular Endothelial Cells: InlB-Dependent Invasion, Long-Term Intracellular Growth, and Spread from Macrophages to Endothelial Cells
- Antibodies Present in Normal Human Serum Inhibit Invasion of Human Brain Microvascular Endothelial Cells by Listeria monocytogenes
- Streptococcus suis Serotype 2 Interactions with Human Brain Microvascular Endothelial Cells
- Interaction of Listeria monocytogenes with mouse dendritic cells.
- Listeria monocytogenes infects human endothelial cells by two distinct mechanisms.