Interference of peptides and specific antibodies with the function of the Actinobacillus pleuropneumoniae transferrin-binding protein.
AUTOR(ES)
Strutzberg, K
RESUMO
Multiple-antigenic peptides (MAPs) containing transferrin-binding domains of the Actinobacillus pleuropneumoniae serotype 7-derived transferrin-binding protein (TfbA) (K. Strutzberg, L. von Olleschik, B. Franz, C. Pyne, M. A. Schmidt, and G.-F. Gerlach, Infect. Immun. 63:3846-3850, 1995) were constructed. It was found that the MAPs inhibited transferrin binding of the recombinant TfbA protein, whereas antibodies directed against transferrin-binding domains failed to do so.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=175771Documentos Relacionados
- Cloning and expression of a transferrin-binding protein from Actinobacillus pleuropneumoniae.
- Mapping of functional regions on the transferrin-binding protein (TfbA) of Actinobacillus pleuropneumoniae.
- Characterization of the diversity and the transferrin-binding domain of gonococcal transferrin-binding protein 2.
- Identification of human transferrin-binding sites within meningococcal transferrin-binding protein B.
- Characterization of two genes encoding distinct transferrin-binding proteins in different Actinobacillus pleuropneumoniae isolates.
