Interferon-gamma inhibits growth of Coxiella burnetii in mouse fibroblasts.
AUTOR(ES)
Turco, J
RESUMO
We studied the effects of various mouse interferon preparations on the growth of Coxiella burnetii in mouse fibroblasts. The addition of both recombinant interferon-gamma and a crude lymphokine preparation that contained interferon-gamma to infected L929 cells inhibited the growth of C. burnetii, whereas the addition of a crude preparation of type I interferons did not. Cycloheximide suppressed the inhibitory effects of recombinant interferon-gamma and crude lymphokines.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=263367Documentos Relacionados
- Recombinant mouse interferon-gamma regulation of antibody production.
- Interferon-gamma inhibits macrophage apolipoprotein E production by posttranslational mechanisms.
- Sequence of the porcine interferon-gamma (IFN-gamma) gene.
- Production of human interferon-gamma in serum-free medium.
- Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.
