Intravitam Diagnosis of Human Rabies by PCR Using Saliva and Cerebrospinal Fluid

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

An optimized reverse transcription (RT)-PCR protocol for the intravitam detection of rabies virus genomic RNA was tested with clinical samples obtained from 28 patients suspected of having rabies, 9 of whom were confirmed to have had rabies by postmortem examination. RT-PCR using saliva combined with an immunofluorescence assay performed with skin biopsy samples allowed detection of rabies in the nine patients.

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