Investigação do papilomavirus humano (HPV) por imuno-histoquimica e hibridização "in situ" em biopsias endoscopicas de esofago

AUTOR(ES)
DATA DE PUBLICAÇÃO

1996

RESUMO

Human Papillomavirus has been describe as a risk factor to benign and malign esophageallesions. The HPV s eommons in esophageal epithelium are 6, 11, 16, 18, 31, 33 and 35. We had select fourty nine endoscopie biopsies which histologic analysis had show koilocytotic atypia in different grades. We has use immunohistochemical and in situ hibridization reactions with commercially biotynilated probes 6/11, 16/18 and 31/33/35 (Viratype probe set.- DIGENE). We couldn t find HPV s antigen or DNA in any fourty nine samples. Then, our studies suggest other factors to development of esophageal tissues alterations.

ASSUNTO(S)

imunohistoquimica esofago - biopsia hibridização in situ virus do papiloma

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