IS6110-Mediated Deletion Polymorphism in Isogenic Strains of Mycobacterium tuberculosis
AUTOR(ES)
Sampson, S. L.
FONTE
American Society for Microbiology
RESUMO
Previous studies have described IS6110-mediated polymorphism as an important driving force in Mycobacterium tuberculosis genome evolution and have provided indirect evidence for IS6110-driven deletion events. This study provides the first description of an IS6110-mediated deletion event in truly isogenic strains. We also provide further support for the hypothesis that the region from Rv1754 to Rv1765 is a hot spot for IS6110 insertion and deletion events.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=344511Documentos Relacionados
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