Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.
AUTOR(ES)
Lane, M A
RESUMO
A cellular transforming gene detected by transfection of mouse T-cell lymphoma DNA has been isolated by molecular cloning. This gene (designated Tlym-I) is homologous to a small conserved family of sequences present in normal mouse and human DNAs but is not related to any of the previously described viral or cellular transforming genes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=345471Documentos Relacionados
- Induction, establishment in vitro, and characterization of functional, antigen-specific, carrier-primed murine T-cell lymphomas.
- Mapping of Specific and Promiscuous HLA-DR-Restricted T-Cell Epitopes on the Plasmodium falciparum 27-Kilodalton Sexual Stage-Specific Antigen
- Heterogeneity of T-cell beta-chain gene rearrangements in human leukaemias and lymphomas.
- E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas.
- Epstein-Barr virus (EBV) gene expression in EBV-positive peripheral T-cell lymphomas.
