Isolation of Inoue-Melnick virus and detection of antibodies in coded cerebrospinal fluid specimens from patients with disorders of the central nervous system.
AUTOR(ES)
Melnick, J L
RESUMO
Inoue-Melnick virus was isolated from coded cerebrospinal fluid samples from 10 of 25 patients with chronic diseases of the central nervous system. Of 13 multiple sclerosis patients and 12 patients with a variety of other symptoms and signs 4 and 6, respectively, were positive. Replicate samples from the same patient yielded the same results, either positive or negative. Neutralizing antibody was present in cerebrospinal fluid at a dilution of 1:25 in the virus-positive patients. Only a single virus-negative patient was positive for antibody at this dilution.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=271761Documentos Relacionados
- Persistence of Inoue-Melnick virus and antibody in cerebrospinal fluid.
- Classification of Inoue-Melnick virus into three antigenic types.
- Inhibitory effect of glucocorticoid hormones on the growth of Inoue-Melnick virus.
- Antibodies in cerebrospinal fluid of some Alzheimer disease patients recognize cholinergic neurons in the rat central nervous system.
- Cerebrospinal fluid concentration of fibronectin in patients with HIV-1 infection and central nervous system disorders.