Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development.
AUTOR(ES)
Noordermeer, J
RESUMO
We have isolated the Xenopus homolog (Xint-1) of the mouse protooncogene int-1 from a neurula stage 17 cDNA library. The deduced protein sequence of Xint-1 includes 371 amino acids. The Xint-1 protein is more similar to the mammalian int-1 product (69%), than to the Drosophila counterpart of int-1, wingless (50%). Xint-1 shares several characteristics of secreted proteins with the other int-1 homologs: it has a hydrophobic leader, multiple conserved potential N-linked glycosylation sites and is rich in cysteine residues. All 23 cysteines are conserved in the three proteins. Xint-1 is transiently expressed during the neurula stages of early Xenopus development.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=331531Documentos Relacionados
- Heat-induced expression of albumin during early stages of rat embryo development.
- Regulation of Raf-1-dependent signaling during early Xenopus development.
- Expression of ribosomal proteins during Drosophila early development.
- Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.
- OCSBF-1, a maize ocs enhancer binding factor: isolation and expression during development.