Killing of Blood-Stage Murine Malaria Parasites by Hydrogen Peroxide

AUTOR(ES)
RESUMO

Both nonlethal Plasmodium yoelii and lethal Plasmodium berghei were killed in vitro by hydrogen peroxide at concentrations as low as 10−5 M. Higher concentrations were required in the presence of added normal erythrocytes. Injection of hydrogen peroxide in vivo significantly reduced P. yoelii parasitemia but had less effect on P. berghei.

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