Lack of reproducibility of macrodilution MBCs for Staphylococcus aureus.
AUTOR(ES)
Pelletier, L L
RESUMO
MBCs of methicillin, oxacillin, penicillin G, cephalothin, vancomycin, and gentamicin were determined by a standard broth macrodilution technique for 101 clinical isolates of methicillin-susceptible Staphylococcus aureus. Increased killing (more than 99.9%) was observed after 48 versus 24 h of incubation for many strains, and cross tolerance to antimicrobial bactericidal activity (less than 99.9% killing) was frequently observed among antimicrobial agents. However, these in vitro measurements of bactericidal activity against S. aureus were not reproducible.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=180030Documentos Relacionados
- MBCs for Staphylococcus aureus as Determined by Macrodilution and Microdilution Techniques
- MBCs for Staphylococcus aureus as determined by macrodilution and microdilution techniques.
- Macrodilution MBC result reproducibility for methicillin-susceptible and reputedly tolerant Staphylococcus aureus isolates.
- Lack of evidence for a saturable tetracycline transport system in Staphylococcus aureus.
- Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus.
