Latent herpes simplex virus type 1 gene expression in ganglia innervating the human gastrointestinal tract.
AUTOR(ES)
Gesser, R M
RESUMO
Using in situ hybridization, we demonstrated that latent herpes simplex virus type 1 (HSV-1) gene expression is prevalent in human adult nodose ganglia. This suggests that infection of gastrointestinal sensory nerves, probably through swallowed virus-laden oral secretions, occurs commonly and that HSV-1 reactivating from this site may play a role in recurrent gastrointestinal disorders.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=191565Documentos Relacionados
- Latent herpes simplex virus type 1 transcription in human trigeminal ganglia.
- Detection by complementation of defective or uninducible (herpes simplex type 1) virus genomes latent in human ganglia.
- Secondary herpes simplex virus latent infection in transplanted ganglia.
- Limited transcription of the herpes simplex virus genome when latent in human sensory ganglia.
- Quantitation of Latent Varicella-Zoster Virus and Herpes Simplex Virus Genomes in Human Trigeminal Ganglia
