LcrG is Required for Efficient Translocation of Yersinia Yop Effector Proteins into Eukaryotic Cells
AUTOR(ES)
Sarker, Mahfuzur R.
FONTE
American Society for Microbiology
RESUMO
Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=108297Documentos Relacionados
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