Legitimate and illegitimate cleavage of human immunodeficiency virus glycoproteins by furin.
AUTOR(ES)
Morikawa, Y
RESUMO
Coexpression of human immunodeficiency virus type 1 glycoproteins with the subtilisin-like protease furin leads to processing of gp160 and gp140, a truncated form of gp160, to gp120. In addition, we show that gp120 itself is further cleaved by furin at sites near the primary cleavage site and within the V3 loop.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=237708Documentos Relacionados
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