Lipopolysaccharide from Klebsiella pneumoniae inhibits Na+ absorption in canine tracheal epithelium.
AUTOR(ES)
Tamaoki, J
RESUMO
The effect of lipopolysaccharide (LPS) from Klebsiella pneumoniae on the bioelectric properties of canine cultured tracheal epithelium was examined. LPS decreased short-circuit current (Isc), and its effects on Isc were reduced when Isc was inhibited by amiloride and indomethacin. We speculate that LPS may selectively inhibit Na+ absorption through the inhibition of prostaglandin synthesis by airway epithelium.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=257818Documentos Relacionados
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