Local immune response in experimental pyelonephritis

AUTOR(ES)

Lehmann, James D.

RESUMO

Experiments using an in vitro method of assessing protein synthesis by 14C amino acid incorporation were designed to determine whether pyelonephritic kidneys were capable of local antibody production. Unilateral pyelonephritis was produced in rabbits by intravenous injection of E. coli 0-75 while one ureter was transiently occluded. The capability of protein and immunoglobulin synthesis by pyelonephritic kidneys, contralateral kidneys, normal kidneys, and spleens from normal and pyelonephritic animals was measured.

Documentos Relacionados

• Local immune response to Escherichia coli pili in experimental pyelonephritis.
• The local immune response to Escherichia coli O and K antigen in experimental pyelonephritis.
• Local immune response to lipoprotein of the outer membrane of Escherichia coli in experimental pyelonephritis.
• Modification by Suppressor Cells and Serum Factors of the Cell-Mediated Immune Response in Experimental Pyelonephritis
• Experimental Escherichia coli ascending pyelonephritis in rats: changes in bacterial properties and the immune response to surface antigens.