Long-term follow up in type A insulin resistant syndrome treated by insulin-like growth factor I.

AUTOR(ES)

Ishihama, H

RESUMO

Insulin-like growth factor I (IGF-I) is a useful therapeutic agent in insulin resistant diabetes mellitus due to insulin receptor disease because of its hypoglycaemic effects through the IGF-I receptor. A girl with typical type A insulin resistant syndrome was treated with IGF-I for two years and the treatment was effective in ameliorating hyperglycaemia. Overproduction of testosterone in polycystic ovaries was aggravated with this treatment, however. Therefore, IGF-I treatment may be used for glycaemic control but with caution because of its possible side effect of aggravating hyperandrogenism in these patients.

Documentos Relacionados

• Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor I.
• Reiter's syndrome: long-term follow-up data.
• The Bedford glaucoma survey. I. Long-term follow-up of borderline cases.
• Long‐term follow‐up of patients with cardiac syndrome X treated by spinal cord stimulation
• Repopulation of the atrophied thymus in diabetic rats by insulin-like growth factor I.