Loss of heterozygosity in lobular carcinoma in situ of the breast

AUTOR(ES)

Lakhani, S R

RESUMO

Aims—(1) To investigate whether loss of heterozygosity identified at various loci in invasive breast carcinoma or is present in lobular carcinoma in situ (LCIS). (2) To investigate whether LCIS is a monoclonal (neoplastic) or a polyclonal (hyperplastic) proliferation.

Documentos Relacionados

• The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
• E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?
• Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified.
• Lobular carcinoma of the breast: a special variant of mucin-secreting carcinoma.
• Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome