Low Temperature and Chloramphenicol Induction of Respiratory Deficiency in a Cold-Sensitive Mutant of Saccharomyces cerevisiae*
AUTOR(ES)
Weislogel, Paul O.
RESUMO
A cold-sensitive mutant of a haploid strain of Saccharomyces cerevisiae has been isolated by selection for impaired growth at 18° on nonfermentable carbon sources. Growth of the mutant on glucose or galactose at either 28 or 18° is similar to that of the parental strain. The cold-sensitive strain is highly mutable to a cytoplasmic petite when grown at 18°, or when grown at 28° in the presence of 4 mg/ml of chloramphenicol. Cold sensitivity is not observed in the conversion of promitochondria to mitochondria. We conclude that mitochondrial protein synthesis is required for maintaining the stability of the mitochondrial genome.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=283165Documentos Relacionados
- Low Temperature and Chloramphenicol Induction of Respiratory Deficiency in a Cold-Sensitive Mutant of Saccharomyces cerevisiae
- Cold-Sensitive Mutation of Pseudomonas putida Affecting Enzyme Synthesis at Low Temperature
- Cold-sensitive mutants of bacteriophage phi-X-174. I. A mutant blocked in the eclipse function at low temperature.
- Cold-Sensitive Mutant of Salmonella typhimurium Defective in Nucleosidediphosphokinase
- Temperature-Dependent Expression of Transformation by a Cold-Sensitive Mutant of Murine Sarcoma Virus
