Maximal Concanavalin A-Specific Agglutinability Without Loss of Density-Dependent Growth Control
AUTOR(ES)
Glynn, Russell D.
RESUMO
Density-inhibited 3T3 mouse fibroblasts were treated for 10 min with nine concentrations of Pronase ranging from 0.25 to 40 μg/ml. Concanavalin A-specific agglutinability increased from control values of about 25% to plateau values of about 80%. None of these Pronase concentrations brought about an increase in cell number within 84 hr. Pronase-treated cells remained responsive to growth stimulation by serum and cortisol. Therefore, the protease-mediated surface change measured by increased concanavalin A-specific agglutinability is not an event sufficient by itself to bring about cell division.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=427081Documentos Relacionados
- Natural Selection and Density-Dependent Population Growth
- Cell density-dependent growth of Myxococcus xanthus on casein.
- Fitness and Density-Dependent Population Growth in DROSOPHILA MELANOGASTER
- Density-dependent regulation of growth of BSC-1 cells in cell culture: control of growth by serum factors.
- Density-dependent Growth Inhibition of Fibroblasts Ectopically Expressing p27kip1
